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澳門新葡官網進入 學校首頁 | 學院首頁 
         
張曉艷

姓名:張曉艷

性別:女

職稱:教授

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招生院所:澳門新葡官網進入

招生類型:博士研究生、碩士研究生

招生專業:藥物分析學(科學學位)

研究方向名稱:生物醫用傳感器研究

電子信箱:xyzhang@ccmu.edu.cn

個人簡介

教授,博士生導師。主要研究方向包括:(1)基于納米電子器件的藥物檢測分析,即利用功能化固態納米器件(場效應晶體管、納米孔等)結合高分子材料修飾技術,應用于超高靈敏度單生物分子及藥物等的檢測和分析;(2)基于人造細胞膜的藥物檢測傳感器,如利用天然膜蛋白重組于固體支撐高分子膜內的活性表面及納米反應器,用于選擇性高靈敏生物分子檢測及分析;(3)功能高分子材料及其生物醫用研究,包括特殊浸潤性抗菌表面、高強度雙網絡水凝膠以及電驅動高分子凝膠作為藥物載體的制備及藥物釋放性能研究。相關研究成果發表在Advanced   Materials、Advanced   Functional Materials、Biomaterials、Small、Chemical   Society Review、Advanced   Science等具有影響力的國際學術期刊上,其中以第一作者或通訊作者發表SCI論文16篇,共計發表論文35篇,影響因子>10的文章7篇,被引用達2000余次,已授權國內專利6項,日本專利2項,美國專利1項。作為獨立PI主持多個國際/國內科研項目,包括瑞士自然科學基金、歐盟瑪麗居麗學者基金,以及中國國家自然科學基金面上項目等。

教育經歷

2005.09 - 2010.07 中國科學院化學研究所高分子物理化學博士

2001.09 - 2005.07 浙江大學材料科學與工程學士

工作經歷

2022.03 - 至今澳門新葡官網進入   教授

2020.09 – 2022.02 清華大學訪問研究員

2016.11 – 2021.08 荷蘭萊頓大學研究員

2010.08 – 2016.10 瑞士巴塞爾大學高分子物理化學博士后

重要學術論文:

1. Xiaoyan Zhang*,   Tingxian Liu, Aimee Boyle, Azadeh Bahreman, Qiushi Jing, Honglei Xue, Roxanne   Kieltyka, Alexander Kros, Grégory F. Schneider*, Wangyang Fu*,   Dielectric-modulated biosensing with ultrahigh-frequency operated graphene   field-effect transistors,  Advanced Materials , 2022,   34(7), DOI:10.1002/adma.202106666. IF="30.7

2. Nianze Shang, Yi Cheng, Shen Ao,   Gulimire Tuerdi, Mengwen Li, Xiaoyu Wang, Hao Hong, Zehui Li, Xiaoyan   Zhang*, Wangyang Fu*, Kaihui Liu*, Zhongfan Liu*, Graphene photonic   crystal fiber-based fluid sensor toward distributed environmental monitoring,    Acta Physico-Chimica Sinica , 2022, 38, 2108041. IF="2.3

3. Gulimire Tuerdi, Abliz Yimit, Xiaoyan   Zhang*, Exploring optical and electrical gas detection based on   zinc-tetraphenylporphyrin sensitizer,  Analytical Sciences , 2022 ,   DOI: 10.1007/s44211-022-00103-9. IF="2.1

4. Yingqi Huang, Shujia Yin, Yujia   Huang, Xiaoyan Zhang, Weizhe Zhang, Guangya Jiang, Q1 Hongwei Zhu,   Chunlei Wan*, Wangyang Fu*, Graphene oxide/hexylamine superlattice   field-effect biochemical sensors,  Advanced Functional Materials , 2021,   31, 2010563. IF="18.8

5. Chunyu Wang, Yue Shao, Kunfeng   Zhang, Baichun Wu, Xianyuan Du, Xingchun Li, Xiaoyan Zhang, Fuxin   Liang*, Zhenzhong Yang*, Facile approach to fabricate a high-performance   superhydrophobic mesh,  ACS Applied Materials and Interfaces , 2021,   13(13), 15720. IF="9.2

6. Xiaoyan Zhang,   Qige Qi, Qiushi Jing, Shen Ao, Zhihong Zhang, Muhong Wu, Kaihui Liu, Weipeng   Wang, Yunhan Ling, Zhengjun Zhang, Wangyang Fu*, Electrical probing of   COVID-19 spike protein receptor binding domain via a graphene field-effect   transistor,  2020 , arXiv:2003.12529 [physics.app-ph].

7. Xiaoyan   Zhang, Pauline van Deursen, Wangyang Fu*, Grégory F.   Schneider*, Facile and ultraclean graphene-on-glass nanopores by controlled   electrochemical etching,  ACS sensors , 2020, 5(8), 2317–2325.   IF="7.7

8. Xiaoyan Zhang,   Qiushi Jing, Shen Ao, Grégory F. Schneider, Dmitry Kireev, Zhengjun Zhang,   Wangyang Fu*, Ultrasensitive field‐effect biosensors enabled by the unique   electronic properties of graphene,  Small , 2020, 16, 1902820.   IF="13.3

9. Serena Rigo, Chao Cai, Gesine   Gunkel-Grabole, Lionel Maurizi, Xiaoyan   Zhang, Jian Xu, Cornelia G. Palivan, Nanoscience‐based strategies to   engineer antimicrobial surfaces,  Advanced   Science , 2018,   5(5), 1700892. IF="16.8

10. Xiaoyan Zhang, Mihai Lomora, Tomaz Einfalt, Wolfgang Meier,   Noreen Klein, Dirk Schneider, Cornelia G. Palivan*, Active surfaces   engineered by immobilizing protein-polymer nanoreactors for selectively   detecting sugar alcohols,  Biomaterials , 2016,   89, 79. IF="12.5

11. Cornelia   G. Palivan*, Roland Goers, Adrian Najer, Xiaoyan Zhang, Anja Car,   Wolfgang Meier*, Bioinspired polymer vesicles and membranes for biological   and medical applications,  Chemical Society Reviews , 2016 ,    45(2), 377-411. IF="54.5

12. Catherine E. Housecroft, Cornelia G. Palivan, Karl Gademann, Michel   Calame, Viktoria Mikhalevich, Xiaoyan Zhang, Ellen Piel, Mathieu Szponarski, Alexandra Wiesler, Angelo Lanzilotto,   Edwin Constable, Axel Fanget, Palph L. Stoop, ‘Active surfaces’ as possible   functional system in detection and chemical (bio) reaction,  CHIMIA   International Journal for Chemistry , 2016, 70(6), 402-412. IF="1.5

13. Justyna Kowal#,   Xiaoyan Zhang# (co-first author), Ionel   Adrian Dinu, Cornelia G. Palivan and Wolfgang Meier, Planar biomimetic   membranes based on amphiphilic block bopolymer,  ACS Macro Letters , 2014,   3, 59-63. IF="6.9

14. Xiaoyan Zhang, Wangyang Fu, Cornelia G. Palivan*, Wolfgang   Meier*, Natural channel proteins inserts and functions in a completely   artificial, solid-supported bilayer membrane,  Scientific Reports ,   2013, 3, 2196. IF="4.4

15. Xiaoyan Zhang, Wangyang Fu, Chunting Duan, Hong Xiao,   Meiwu Shi, Ning Zhao*, Jian Xu*, Superhydrophobicity determines the buoyancy   performance of kapok fiber aggregates,  Applied Surface Science , 2013, 266, 225. IF="6.7

16. Cornelia G. Palivan*, Xiaoyan Zhang, Wolfgang Meier*,   Protein–polymer supramolecular assemblies: a key combination for   multifunctionality,  Chimia , 2013, 87, 791-795. IF="1.5

17. Christoph   Edlinger, Xiaoyan Zhang, Ozana   Fischer-Onaca, Cornelia G. Palivan, Polymer nanoreactors,  Encyclopedia of polymer science and   technology , 2013,   581.

18. Chunting Duan, Ning Zhao*,   Xiaolan Yu, Xiaoyan Zhang, Jian   Xu*, Chemically modified kapok fiber for fast adsorption of Pb2+, Cd2+, Cu2+   from aqueous solution,  Cellulose ,   2013, 20(2), 849–860. IF="5.0

19. Xiaoyan Zhang, Pascal Tanner, Alex Graff, Cornelia Palivan*,   Wolfgang Meier, Mimicking the cell membrane with block copolymer membranes,  Journal of Polymer Science, Part A: Polymer   Chemistry , 2012, 50(12), 2293. IF="2.7

20. Etienne   Cabane#, Xiaoyan   Zhang# (co-first   author), Karolina   Langowska, Cornelia Palivan*, Wolfgang Meier, Stimuli-responsive polymers and   their applications in nanomedicine,  Biointerphases , 2012,   7(1-4), 9. IF="2.5

21. Haosen Fan, Xiaolan Yu, Yuhua   Long, Xiaoyan Zhang, Haifan Xiang,   Chunting Duan, Ning Zhao, Xiaoli Zhang, Jian Xu*, Preparation of   kapok–polyacrylonitrile core–shell composite microtube and its application as   gold nanoparticles carrier.  Applied   Surface Science , 2012,   258, 2876-2882. IF="6.7

22. Xiaoyan Zhang,   Yanfang Li, Shuguang Yang, Ning Zhao, Lianghe Shi, Hong Xiao, Meiwu Shi,   Xiaoli Zhang, Jian Xu*, Facile fabrication of large scale microtubes with a   natural template—kapok fiber,  Chinese Journal of Polymer Science , 2010, 28(5),   841. IF="3.6

23. Liang Zhang, Xiaoyan Zhang, Zhen Dai, Junjie Wu, Ning Zhao, Jian Xu*,   Micro-nano hierarchically structured nylon 66 surfaces with unique   wettability,  Journal of Colloid   and Interface Science , 2010,   345, 116-119. IF="8.1

24. Junjie Wu, Songmiao Liang,   Hongjun Dai, Xiaoyan Zhang,   Xiaolan Yu, Yuanli Cai, Lina Zhang, Ning Wen, Bin Jiang, Jian Xu*, Structure   and properties of cellulose/chitin blended hydrogel membranes fabricated via   a solution pre-gelation technique,  Carbohydrate   Polymers , 2010, 79,   677-684. IF="9.4

25. Xiaoyan Zhang,   Xinglin Guo, Shuguang Yang, Shuaixia Tan, Xiaofeng Li, Hongjun Dai, Xiaolan   Yu, Xiaoli Zhang, Ning Weng, Bin Jian, Jian Xu*, A double-network hydrogel   with high mechanical strength prepared by two biocompatible polymers,  Journal   of Applied Polymer Science , 2009, 112(15), 3063. IF="3.1

26. Xiaofeng Li, Hongjun Da, Shuaixia   Tan, Xiaoyan Zhang, Haiyun Liu,   Yongxin Wang, Ning Zhao, Jian Xu*, Facile preparation of poly(ethyl   a-cyanoacrylate) superhydrophobic and gradient wetting surfaces,  Journal of Colloid and Interface Science ,   2009, 340, 93–97. IF="8.1

27. Xiaoyan Zhang,   Ning Zhao, Songmiao Liang, Xiaoying Lu, Xiaofeng Li, Qiongdan Xie, Xiaoli   Zhang, Jian Xu*, Facile creation of biomimetic systems at the interface and   in bulk,  Advanced Materials , 2008, 20, 2938. IF="30.7

28. Ning Zhao, Xiaoyan Zhang,   Xiaoli Zhang, Jian Xu*, Simultaneous tuning chemical composition and   topography of copolymer surface: micelles as the building blocks,  ChemPhysChem , 2007, 8, 1108-1114. IF="3.1

29. Ning   Zhao, Xiaoyan   Zhang, Yanfang Li, Xiaoying Lu, Silu Sheng, Xiaoli Zhang, Jian Xu*, A   self-organized polymer aggregates with a biomimetic hierarchical structure   and its superhydrophobic effect,  Cell   Biochemistry and Biophysics , 2007,   49, 91-97. IF="2.2

30. Shuaixia   Tan,   Xiaoyan Zhang, Ning Zhao, Xinglin   Guo, Xiaoli Zhang, Jian Xu*,   Simulation of sessile water-droplet evaporation on superhydrophobic surfaces,    Chinese Journal of Chemical Physics ,   2007, 20(2), 140-144. IF="1.1

31. Ning Zhao, Xiaoying Lu, Xiaoyan Zhang, Shuaixia Tan, Haiyun Liu,   Jian Xu*, Progress in superhydrophobic surfaces,  Progress   in Chemistry ,   2007, 19, 860. IF="1.2

32. Shuguang Yang, Yongjun Zhang, Xiaoyan Zhang, Ying Guan, Jian Xu*, Xiaoli   Zhang, From cloudy to transparent: chain rearrangement in hydrogen-bonded   assembly film,  ChemPhysChem ,   2007, 8, 418-424. IF="3.1

33. Xiaoyan Zhang,   Shuaixia Tan, Ning Zhao, Xinglin Guo, Xiaoli Zhang, Yongjun Zhang, Jian Xu*,   Evaporation of sessile water-droplet on natural lotus and biomimetic polymer   surface with superhydrophobicity,  ChemPhysChem , 2006,   7(10), 2067. IF="3.1

34. Ning Zhao, Lihui Weng,   Xiaoyan Zhang, Qiongdan Xie, Xiaoli Zhang, Jian Xu*, A lotus-leaf-like   superhydrophobic surface prepared by solvent-induced crystallization,  ChemPhysChem , 2006, 7, 824-827. IF="3.1

35. Ning Zhao, Qiongdan Xie, Lihui   Weng, Shengqing Wang, Xiaoyan Zhang,   Jian Xu*, Superhydrophobic surface from vapor-induced phase separation of   copolymer micellar solution,  Macromolecules , 2005,  38,    8996-8999. IF="5.9

承擔重要項目

1. 52173007,基于Janus磁性蛋白復合體調控仿細胞膜定向傳輸及開關功能的研究,國家自然科學基金,面上項目,58萬元(2022.01-2025.12)

2. 20212001392,清華大學,技術服務項目,生物化學傳感器的測試與優化,40萬元,(2021.09-2022.03)

3. 749671,Advanced graphene   nanodevices with functional hydrogels for DNA sequencing,European Commission,Marie-Sk?odowska-Curie   Individual Fellowship,192599 Euro(2018.10-2020.08)

4. P300P2-164663,Slowing down DNA   translocation through graphene nanopore with functional hydrogel,Swiss National Science   Foundation,Advanced Postdoc.Mobility Fellowship,98400 Swiss Franc(2016.11-2018.09)

重要獎項

1. 張曉艷,瑪麗居里學者,國家級,擇優,歐洲學術委員會,2017

2. 張曉艷,APM學者,國家級,擇優,瑞士國家科學基金委員會,2016

3. 張曉艷,北京市“海聚工程”,省部級,全職項目,北京市教育委員會,2022



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